"Right now we have no additional strikes planned", he said. But the escalation dynamic is entirely in Assad's control: If he wants to use more chemical weapons, the USA will either have to respond yet again or be seen as giving Assad (and other dictators) a green light to use chemical weapons on their own people.
What is the crisis about?
On Saturday, Putin reaffirmed Russia's view that a purported chemical attack in the Syrian town of Douma that prompted the strike was a fake.
Syrian state-run television reported that three civilians had been wounded in the missile attack on a military base in the city of Homs.
A day before a team from the worldwide chemical weapons watchdog was to arrive in Douma, just east of Damascus, Russian Defence Ministry spokesman Major General Igor Konashenkov said that images of victims of the purported attack were staged with "Britain's direct involvement", without providing evidence.
The comments came after Russian Federation accused the United Kingdom of "staging" the chemical weapons attacks in Douma, the last rebel-held enclave of eastern Ghouta on the outskirts of Damascus.
Further, referring to Assad, he said, "These are not the actions of a man".
Russian Foreign Minister Sergei Lavrov said the latest suspected attack was staged by foreign agents. It was not known if U.S pilots were flying over Syrian airspace, however, Mattis did say "manned aircraft" were involved in the airstrikes.
Reports circulated that the Dumayr air base outside Damascus was one of the other targets hit.
This is the first time as Prime Minister that I have had to take the decision to commit our armed forces in combat - and it is not a decision I have taken lightly.
How many missiles were fired? . "Get ready Russian Federation, because they will be coming, nice and new and 'smart!' You shouldn't be partners with a Gas Killing Animal who kills his people and enjoys it!"
"They were in closed spaces, sheltering from the barrel bombs, which may have caused their quick death as no-one heard their screams".
A senior administration official said "what you've seen tonight is not the end of the U.S. response".
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Trump told Moscow on Wednesday to "get ready" for an American missile strike in Syria, after a Kremlin diplomat said that any rockets aimed toward Russian forces there - as well as any plane or ship that fired them - would be targeted. The second target was a chemical weapons storage facility west of Homs. More details are expected Saturday.
Iran's Fars News Agency reported Friday that Russian fighter jets were patrolling Syrian air space to defend against any attackers.
The departure of USA troops, military strategists say, will probably pave the way for Assad's consolidation of control in the country, backed by Russia, Iran, and the Lebanese militia Hezbollah.
The continuing involvement of American forces in Syria, Iraq and Afghanistan, where the USA has fought extended conflicts since September 11, 2001, continues to be a source of consternation for him.
Syrian government forces had taken precautions at military bases throughout the week in anticipation of possible strikes.
Other Tory MPs also publicly voiced their support, with Thornbury and Yate MP Luke Hall saying: "Speed is essential".
A boy walks through war-torn Douma, Eastern Ghouta, outside of Damascus, Syria, last month.
It could bring into play the advanced, but as yet untested, S-400 air defence system.
The Pentagon could not confirm how many missiles hit their targets.
The UK has eight supersonic Tornados stationed in Cyprus and RAF Typhoons have also been operating in the region.
Sablin advised "the Western adventurists who have unleashed aggression in the Middle East again to turn an attentive ear to the warning from the chief of Russia's General Staff Valery Gerasimov such aggression would not remain unretaliated". The UK's Rivet Joint surveillance aircraft are also available.
In that strike, 59 Tomahawk cruise missiles were launched from the USS Ross and USS Porter in the Mediterranean.
With its nuclear-powered Charles de Gaulle aircraft carrier undergoing refitting, France has deployed sailors and aviators on board the USA aircraft carrier USS George HW Bush for training and joint operations.