On Friday, two protesters were shot dead in skirmishes with Israeli troops along Gaza's border.
Islamic Jihad's armed wing said two of its members were killed, Haaretz reported.
The two men were reportedly riding through the town of Beit Lahiya on Tuesday when their motorcycle exploded.
Diggers are seen near the area where the Israeli forces said a "significant" cross-border attack tunnel from the Gaza Strip, which was being dug by the enclave's dominant Islamist group, Hamas, was destroyed, near Israel's border with the Gaza Strip December 10, 2017.
Shortly after midnight on Tuesday, Israeli forces attacked Hamas targets in the northern Gaza Strip after Palestinians fired a rocket toward the southern city of Ashkelon, the army said.
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The rocket, fired at about 11:30 p.m., triggered early warning sirens in Ashkelon, the Lachish region and in the area around the Gaza Strip.
This was the second round of Palestinian rocket fire and Israeli responses in a day. The Iron Dome Aerial Defense System intercepted a rocket above the city. The IDF is not yet saying if additional rockets were launched or not.
Tensions along the Israel-Gaza border are high following a week of rocket fire and clashes between Israeli security forces and Palestinians in the wake of US President Donald Trump's decision to recognize Jerusalem as the capital of Israel. "The IDF holds Hamas responsible for these aggressive acts originating from the Gaza Strip".
A senior security establishment official is quoted anonymously telling Walla News on Shabbos that "Hamas is playing a risky game as Israel views renewed rocket fire from Gaza a very serious".
In the process of that demolition, 10 gunmen from the group and another two from Hamas were killed - deaths that Israeli sources described as an unintended result of the passage's collapse within Gazan turf.