Health-care workers play a critical role in the delivery of care to people with a high risk of flu-related complications, such as babies, young children, seniors and people with compromised immune systems, they said in an email.
The World Health Organization estimates the flu virus results in 1 billion infections, 3 to 5 million cases of severe disease and 300,000 to 500,000 deaths annually. You can have some side effects after vaccination, but this is not flu illness. For over 70 years, the flu vaccine has been made by injecting strains of the flu virus into chicken eggs.
Why the flu vaccine may not be as effective as we believe Of course, we know that flu viruses mutate, and we have seen examples of this happening, especially in bird flu viruses.
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"Even influenza vaccine manufacturers are recognizing that, over time, the egg-based production process will become obsolete and will be replaced with a more modern production process", she said. They only know at the end of the season if their vaccine was a good match. Current vaccines, which require experts to pick the flu strains that they believe are going to circulate in a given year, are typically 40 to 70 percent effective in the US, though in some years protection is as low as 20 percent. The 2016-2017 vaccine was only 43 percent effective against the predominant influenza A H3N2 strain, and protection has been nearly as low in other years. Scientists are trying various approaches to better match vaccines to multiple viral strains. "During the 2014-2015 influenza season, clade 3C.2a H3N2 viruses possessing a new predicted glycosylation site in antigenic site B of HA emerged, and these viruses remain prevalent today", wrote the article's authors.
However, as the study was done on mice, more research needs to be conducted to determine if the vaccine works in human.
"Our experiments suggest that antigens of the influenza virus grown in systems other than eggs are probably more likely to trigger an immune response by producing neutralizing antibodies to the H3N2 viruses in circulation", said professor Hensley. The vaccine is made from an inactivated virus that can not transmit infection. You can't get the flu from the shot because the vaccine contains viruses that are inactivated or severely weakened.