Bugti said a forensic team and the Bomb Disposal Squad had been called to the site to investigate the nature of the blast.
Security forces have already cordoned off the area. For over a decade, Balochistan, Pakistan's mineral-rich and largest province by area, has been gripped by a homegrown separatist insurgency and religious terrorism.
Civil Hospital Quetta Spokesperson Wasim Baig confirmed seven casualties and said that injured had been brought to the medical facility where emergency has been imposed, the report said.
The injured have been shifted to Jinnah Hospital.
He said the war against terrorism was not over and would go on until the last terrorist was eliminated. "Balochistan is on the forefront of this fight and we will not stop until there is not a single terrorist left in the area", Bugti said.
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He added: "These cowardly attacks will not hinder our security forces in executing their duties".
Baloshistan has witnessed several blasts and targeted killings in the past few months.
Talking to media following an explosion on the Sibi road Home Minister said that they are in the state of war and Pakistan is fighting with bravery the war against militants and Inshallah we will emerge victorious.
A police official in Quetta gave a different toll, putting the figures at seven dead and 10 wounded, and said the attack came as the police were commuting to work.
The group of elite police were targeted on the Sariab road in the outskirts of Quetta, capital of Balochistan province, as they headed to work.