Ronaldo, Real's all-time leading scorer, passed a new club milestone on Sunday after scoring his 400th and 401st competitive goals in the 4-1 victory over Sevilla.
Madrid remain in the driving seat after the European champions saw off Sevilla 4-1 as they have two games remaining to Barca's one.
Real's game in hand comes at Celta on Wednesday in a match postponed from February due to storm damage at Celta's Balaidos stadium.
"It is a long road".
"James is here [now] and we have a long way to go yet", Zidane said.
"We never gave up, we were very regular in the second round of play and that allowed the football players to be rewarded again with clinching a direct passage to the Champions League".
Real would then be able to turn their attention to next month's Champions League final against Juventus with confidence sky high, but Zidane is determined not to look too far ahead.
"Each day we are getting closer and with two games left we are going to continue in the same vein".
Real Madrid took on Sevilla in the Bernabeu on Sunday night and, with his side 2-1 up at the time, Rodriguez was withdrawn from the field in the 60th minute.
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Whatever happens in Vigo, the title will be decided in the final round of games next weekend after Barcelona's rousing victory in the Canary Islands.
Ronaldo made it 2-0 with an easy tap-in for his landmark goal.
Undoubtedly his second strike was the pick of the goals.
Sevilla responded to falling behind by hitting the post, Stevan Jovetic's effort crashing back off the frame of the goal before Real doubled their lead on 23 minutes. There was still time for Kroos to get on the score sheet, with the Germany global finding the bottom corner in the 84th minute.
After a quiet start to the half, Betis broke the deadlock in the 57th minute courtesy of a superb strike from Dani Ceballos, who beat Oblak with a powerful volley from 25-yards out.
After wonderful passes from Sergio Busquets and Andres Iniesta, Suarez squared for Neymar to open the scoring.
The Colombia worldwide came off just past the hour-mark and applauded the Madrid fans, but Nacho does not think it was a farewell.
And Neymar completed his hat trick soon after, tucking the ball home after being found by Jordi Alba, to put the game out of sight.